Drugs That Interfere With Prometrium

Barbiturates
Barbiturates may cause your body to metabolize the hormones in Prometrium too quickly, which could make Prometrium less effective. Let your healthcare provider know if you notice a decrease in Prometrium's effectiveness while taking a barbiturate.
 
Modafinil (Provigil)
Modafinil may make Prometrium less effective. Let your healthcare provider know if you notice a decrease in Prometrium's effectiveness while taking modafinil.
 

Final Thoughts on Prometrium Drug Interactions

It is possible that not every drug interaction with Prometrium was discussed in this article. Therefore, you should talk with your pharmacist or healthcare provider about the drug interactions that may apply to you.
 
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Prometrium Medication Information

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