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Prometrium Dosage
Your particular dosage of Prometrium will depend on what the drug is being used to treat. For example, the recommended dose for causing a menstrual period is 400 mg once daily for ten days. When used for hormone replacement in postmenopausal women, the recommended Prometrium dosage is 200 mg a day for 12 days in a row.
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The dose of Prometrium® (progesterone capsules) your healthcare provider recommends will vary, depending on a number of factors, including:
- The medical condition being treated
- Other medical conditions you may have.
As always, do not adjust your dosage unless your healthcare provider specifically instructs you to do so.
When used to cause a menstrual period, the recommended Prometrium dosage is 400 mg, taken once daily at bedtime for ten days. A period usually starts within seven days after the last dose. If your period has not started after a week, let your healthcare provider know.
Prometrium is also approved to be used in combination with estrogen medications for hormone replacement in postmenopausal women. For this use, Prometrium dosing guidelines call for 200 mg, taken once daily at bedtime for 12 days in a row during each 28-day estrogen cycle. You may not have a regular menstrual period when you take the drug in this manner.
Prometrium is often used as progesterone supplementation during pregnancy, even though it is not approved for this use. As a result, there are no official guidelines for dosing Prometrium during pregnancy. Consult your healthcare provider for specific information about what dose you should take during pregnancy.
Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD



