Prempro Warnings and Precautions

Before using Prempro, warnings and precautions for the medication should be reviewed with your healthcare provider. For example, make sure your healthcare provider is aware of any existing medical conditions you have, such as heart disease, diabetes, or kidney disease. Prempro warnings and precautions also include knowing that the drug may increase your risk of developing breast cancer, gallbladder disease, or dementia.

Prempro Drug Information

Prempro: What Should I Tell My Healthcare Provider?

You should talk with your healthcare provider prior to using Prempro™ (conjugated estrogens/medroxyprogesterone) if you have:

A history of blood clots
Cancer (or if you have had cancer in the past)
A history of heart attack or stroke
Heart disease
High blood pressure (hypertension)
High cholesterol or high triglycerides
Liver disease, such as liver failure, cirrhosis, hepatitis, or liver tumors
Systemic lupus erythematosus (SLE or lupus)
Kidney disease, including kidney failure (renal failure)
Congestive heart failure (CHF)
Diabetes
Yellowing of the whites of the eyes or skin (jaundice) during a prior pregnancy or estrogen use
Gallbladder disease
An underactive thyroid (hypothyroidism)
Endometriosis
Unexplained vaginal bleeding
Any allergies, including allergies to drugs, foods, preservatives, or dyes.

Also, let your healthcare provider know if you:

Have an upcoming surgery
Smoke cigarettes
Are pregnant or thinking of becoming pregnant
Are breastfeeding.

Make sure to tell your healthcare provider about any other medicines you are taking, including prescription and non-prescription medicines, vitamins, and herbal supplements.

(Prempro Warnings and Precautions Continued: Page 2)