There are various Prempro uses, such as treating certain menopausal symptoms and preventing osteoporosis in postmenopausal women. This prescription hormone medication contains a mixture of natural estrogens and a progestin hormone. The progestin hormone helps decrease the risk of developing cancer of the lining of the uterus. For women without a uterus, the progestin component is usually considered unnecessary.
Prempro Uses: An OverviewPrempro™ (conjugated estrogens/medroxyprogesterone) is a prescription hormone medication that contains a mixture of natural estrogens combined with a progestin hormone. Prempro is approved for the following uses:
- Treatment of moderate to severe itching, burning, or dryness in or around the vagina due to menopause
- Treatment of moderate to severe hot flashes due to menopause
- Prevention of osteoporosis in postmenopausal women.
In all cases, Prempro is only approved for women who still have a uterus (those who have not had a hysterectomy). If you have had a hysterectomy, the medroxyprogesterone component of the drug is usually considered unnecessary.
Prempro Uses for MenopauseMenopause is a normal change in a woman's life when she stops having her period. That's why some people call menopause "the change of life." A woman has reached menopause when she has not had a period for 12 months in a row and there are no other causes for this change. Symptoms of menopause include:
- Hot flashes (sometimes known as hot flushes)
- Vaginal changes, such as dryness or irritation
- Changes in your period, including abnormal bleeding or "spotting"
- Night sweats and sleeping problems (including insomnia)
- Thinning and weakening of your bones
- Mood changes
- Urinary problems
- Problems with concentration or memory
- Less interest in sex and changes in sexual response
- Weight gain or an increase in body fat around your waist
- Hair thinning or loss.
For some women, these symptoms are quite severe and some form of menopause relief may be necessary. This may include medications, natural menopause relief remedies, or non-medical ways to deal with the symptoms.
During and after menopause, women experience a drop in estrogen levels, as well as a shift in the balance of estrogens that the body produces. Before menopause, the ovaries produce the main source of estrogen, and the main type of estrogen produced is known as estradiol. After menopause, the main source of estrogen is androstenedione, which is produced by the adrenal gland and is converted into an estrogen known as estrone. Menopausal symptoms and changes result from the decrease in estrogen and the shift from estradiol to estrone. Prempro contains a mixture of natural equine (horse) estrogens. It helps to relieve menopausal symptoms by replacing the estrogen that the ovaries no longer produce.
In addition to estrogen, Prempro contains medroxyprogesterone, a progestin hormone. Medroxyprogesterone is added to Prempro because giving estrogens without a progestin to postmenopausal women can increase the risk of cancer of the lining of the uterus. Of course, this applies only to women who still have a uterus (who have not had a hysterectomy). For women without a uterus, the medroxyprogesterone component is considered unnecessary.
When used to treat menopause, Prempro should be used at the lowest effective dose for the shortest period necessary.
Prempro is a continuous (not cyclic) hormone replacement therapy (HRT) medication. In other words, it is taken nonstop, without any breaks from either of the hormones.