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Problems With Premphase to Watch For
Serious Premphase Side Effects
Some side effects of Premphase are rare, but are serious enough to mention. These side effects include:- Blood clots
- Dementia
- Anxiety
- Breast cancer or ovarian cancer
- Stroke
- Heart attack
- Depression
- Gallbladder disease
- Allergic reactions.
Because of the serious nature of these side effects, there are a few symptoms you should watch out for report to your healthcare provider immediately if they occur. These include but are not limited to:
- Signs of a blood clot in the leg, such as:
- Pain in the calf
- Leg cramps
- Leg or foot swelling
- Signs of a blood clot in the lung, such as:
- Shortness of breath
- Sharp chest pain
- Coughing up blood
- Chest pain or heaviness, which may be signs of a heart attack
- Signs of a stroke, such as:
- Vision or speech changes
- Weakness or numbness in an arm or leg
- Severe headache
- Signs of liver damage, such as:
- Yellowing of the whites of the eyes or skin (jaundice)
- Dark urine
- Upper-right abdominal pain (stomach pain)
- Migraines (or changes in your migraines, if you have had them before)
- Breast lumps
- Sudden loss of vision or vision changes, which can be a sign of a blood clot in the eye
- Heavy vaginal bleeding or unexpected vaginal bleeding
- Signs of an allergic reaction, such as:
- An unexplained rash
- Hives
- Itching
- Unexplained swelling
- Wheezing
- Difficulty breathing or swallowing.
Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD