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Premarin Warnings and Precautions
Although Premarin has several beneficial effects, it may not be suitable for everyone. For instance, you may not be able to take Premarin if you have high blood pressure, diabetes, congestive heart failure, or certain other conditions. Other Premarin warnings and precautions also apply to people who have certain allergies and to women who are pregnant or breastfeeding.
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You should talk with your healthcare provider prior to using Premarin® (conjugated estrogens) if you have:
- Had a heart attack or stroke
- Heart disease
- Had a blood clot
- High blood pressure (hypertension)
- High cholesterol
- Diabetes
- Had yellowing of the whites of the eyes or skin (jaundice) during a prior pregnancy or estrogen use
- High cholesterol
- Gallbladder disease
- Liver disease, such as liver failure, cirrhosis, hepatitis, or liver tumors
- Kidney disease, including kidney failure (renal failure)
- Congestive heart failure (CHF)
- An underactive thyroid (hypothyroidism)
- Low calcium levels in the blood (hypocalcemia)
- Endometriosis
- Cancer (or if you have had cancer in the past)
- Unexplained vaginal bleeding
- Any allergies, including allergies to drugs, foods, preservatives, or dyes.
Also, let your healthcare provider know if you:
- Have an upcoming surgery
- Smoke cigarettes
- Are pregnant or thinking of becoming pregnant
- Are breastfeeding.
Make sure to tell your healthcare provider about any other medicines you are taking, including prescription and non-prescription medicines, vitamins, and herbal supplements.
Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD