There are several Premarin uses, such as treating menopausal symptoms, treating hormone deficiency in younger women, and relieving the symptoms of certain cancers. This prescription hormone medication contains a mixture of natural estrogens. Because using Premarin without a progesterone can increase the risk of cancerous changes in the uterus, it must be combined with a progesterone in women who still have a uterus.
What Is Premarin Used For?Premarin® (conjugated estrogens) is a prescription hormone medication that contains a mixture of natural estrogens. It does not, however, contain any progesterone hormones. Premarin is approved for the following uses:
- Treatment of menopausal symptoms, such as hot flashes and vaginal dryness
- Prevention of osteoporosis in postmenopausal women
- Treatment of hormone deficiency in younger women whose ovaries do not produce enough estrogen
- Relief of symptoms of certain cancers (in both men and women) that have spread throughout the body.
Using Premarin for Menopause
Menopause is a normal change in a woman's life when she stops having her period. That's why some people call menopause "the change of life." A woman has reached menopause when she has not had a period for 12 months in a row and there are no other causes for this change. Menopause symptoms include:
- Changes in your period, including abnormal bleeding or "spotting"
- Hot flashes (hot flushes)
- Night sweats and sleeping problems (including insomnia)
- Vaginal changes, such as dryness or irritation
- Thinning and weakening of your bones
- Mood changes
- Urinary problems
- Problems with concentration or memory
- Less interest in sex and changes in sexual response
- Weight gain or increase in body fat around your waist
- Hair thinning or loss.
For some women, these symptoms are quite severe, and some form of menopause relief may be necessary. This may include medications, natural menopause relief remedies, or non-medical ways to deal with the symptoms.
During and after menopause, women experience a drop in estrogen levels, as well as a shift in the balance of estrogens that the body produces. Before menopause, the main source of estrogen is produced by the ovaries, and the main type of estrogen produced is known as estradiol. After menopause, the main source of estrogen is androstenedione, which is produced by the adrenal gland and is converted into an estrogen known as estrone. Menopausal symptoms and changes result from both the estrogen decrease and the shift from estradiol to estrone. Premarin is a mixture of natural equine (horse) estrogens. It helps to relieve menopausal symptoms by replacing the estrogen that the ovaries no longer produce.
For menopause treatment, Premarin should be used at the lowest effective dose for the shortest period necessary.
Because Premarin (or any other estrogen treatment) without progesterone can increase the risk of precancerous or cancerous changes in the uterus, it must be combined with a progestin (either continuously or intermittently) in women who still have a uterus. If you have had a hysterectomy, you can take Premarin alone, without any progesterone.