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Reviewing Premarin Safety Concerns
Drug Interactions With Premarin
Premarin can interact with several other medications (see Premarin Drug Interactions).What Should I Tell My Healthcare Provider?
You should talk with your healthcare provider prior to using this medication if you have:- Had a heart attack or stroke
- Heart disease
- Had a blood clot
- A clotting disorder
- High blood pressure (hypertension)
- High cholesterol
- Diabetes
- Had yellowing of the whites of the eyes or skin (jaundice) during a prior pregnancy or estrogen use
- High cholesterol
- Gallbladder disease
- Liver disease, such as liver failure, cirrhosis, hepatitis, or liver tumors
- Kidney disease, including kidney failure (renal failure)
- Congestive heart failure (CHF)
- An underactive thyroid (hypothyroidism)
- Low calcium levels in the blood (hypocalcemia)
- Endometriosis
- Cancer (or if you have had cancer in the past)
- Unexplained vaginal bleeding
- Any allergies, including allergies to drugs, foods, preservatives, or dyes.
Also, let your healthcare provider know if you:
- Have an upcoming surgery
- Smoke cigarettes
- Are pregnant or thinking of becoming pregnant (see Premarin and Pregnancy)
- Are breastfeeding (see Premarin and Breastfeeding).
Make sure to tell your healthcare provider about any other medicines you are taking, including prescription and non-prescription medicines, vitamins, and herbal supplements.
(Click Premarin Warnings and Precautions to learn more, including information on who should not take the drug.)
Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD