Premarin and Weight Gain

Clinical studies have shown that there is probably not a connection between Premarin and weight gain for most women. Although women often gain weight while taking Premarin, it appears that this weight gain is probably due to other factors (such as a poor diet and inactivity). If you are taking Premarin and weight gain becomes a problem, you can try eating a heart-healthy diet, limiting your alcohol intake, and exercising more frequently.

Does Premarin Cause Weight Gain?

Premarin® (conjugated estrogens) is a prescription estrogen medication. Contrary to popular belief, Premarin probably does not cause weight gain for most women.

Premarin, Weight Gain, and Clinical Studies

In general, clinical studies have shown that Premarin probably does not cause weight gain. Although women taking Premarin often gain weight, it appears that this weight gain is probably not caused by the medication. In several studies, there were no significant differences in weight gain between women who took Premarin and those who did not. While it may be easy to blame weight gain on Premarin, the real causes of such weight gain are probably due to a poor diet, inactivity, and other factors.
However, hormones can occasionally cause water retention. Because weight gain (especially rapid weight gain) is a sign of fluid retention, it is possible that Premarin could cause water weight gain. While this is not usually dangerous, it can cause problems in some people (such as those with congestive heart failure, or CHF).

Premarin and Weight Gain: Suggestions

If you are noticing unexplained and undesired weight gain while taking Premarin, there are a few things that you can do to get your weight back under control. Some suggestions include:
  • Participating in regular physical activity for at least 30 minutes a day on most days of the week.
  • Eating a heart-healthy diet. This diet should include:


    • Lots of fruits, vegetables, grains, and fat-free or low-fat milk and milk products
    • Lean meats, poultry, fish, beans, eggs, and nuts
    • Limited amounts of saturated fats, trans fats, cholesterol, sodium (salt), and added sugars. 


  • Limiting your intake of alcohol or other "empty" calories (such as full-sugar soda, candy, and sweets).
Remember, quick fixes (such as weight loss pills) are usually not the answer. The best weight loss plans aim for moderate, steady weight loss through diet and exercise.
Also, if you are noticing weight gain with Premarin, talk to your healthcare provider. He or she can give you other suggestions for dealing with any weight gain. He or she may also look for other causes of weight gain, such as certain types of medical conditions. If the weight gain continues, your healthcare provider may also suggest other lifestyle changes or recommend another menopause treatment.
(Click BMI Calculator to see if your weight is within a healthy range.)
Men and Osteoporosis

Premarin Drug Information

Referring Pages:
Terms of Use
Advertise with Us
Contact Us
About eMedTV
Privacy Policy
Copyright © 2006-2020 Clinaero, Inc.
eMedTV serves only as an informational resource. This site does not dispense medical advice or advice of any kind. Site users seeking medical advice about their specific situation should consult with their own physician. Click Terms of Use for more information.