Premarin Vaginal Cream Warnings and Precautions

Several potential risks are associated with Premarin Vaginal Cream. Warnings and precautions for this medication should be fully understood before starting treatment. For instance, you may not be able to safely use the cream if you have heart disease, liver disease, or an underactive thyroid. Premarin Vaginal Cream warnings and precautions also apply to women who are pregnant or breastfeeding.

Premarin Vaginal Cream Information

Premarin Vaginal Cream: What Should I Tell My Healthcare Provider?

You should talk with your healthcare provider prior to using Premarin^®Vaginal Cream (conjugated estrogens vaginal cream) if you have:

A history of blood clots
A history of heart attack or stroke
Heart disease
High blood pressure (hypertension)
High cholesterol
Liver disease, such as liver failure, cirrhosis, hepatitis, or liver tumors
Kidney disease, including kidney failure (renal failure)
Diabetes
Had yellowing of the whites of the eyes or skin (jaundice) during a prior pregnancy or estrogen use
High cholesterol
Gallbladder disease
Congestive heart failure (CHF)
An underactive thyroid (hypothyroidism)
Low calcium levels in the blood (hypocalcemia)
Endometriosis
Cancer (or if you have had cancer in the past)
Unexplained vaginal bleeding
Any allergies, including allergies to drugs, foods, preservatives, or dyes.

Also, let your healthcare provider know if you:

Have an upcoming surgery
Are pregnant or thinking of becoming pregnant
Are breastfeeding
Smoke cigarettes.

Make sure to tell your healthcare provider about any other medicines you are taking, including prescription and non-prescription medicines, vitamins, and herbal supplements.

(Premarin Vaginal Cream Warnings and Precautions Continued: Page 2)