Pregnenolone Side Effects

Although pregnenolone is a "natural" product, it is not necessarily free of side effects. Pregnenolone can cause problems such as insomnia, headaches, and hair loss. These may not seem serious, but can be a sign of a hormonal imbalance that could lead to more serious problems. Therefore, if you experience any possible side effects, make sure to contact your healthcare provider.

Side Effects of Pregnenolone: An Overview

Just like any medication or supplement, pregnenolone can cause side effects. People often assume that natural products are free of side effects, especially dangerous ones. However, this is simply not the case. It should be assumed that any supplement potent enough for medicinal use is capable of causing side effects.
(This article covers many, but not all, of the possible side effects with pregnenolone. Your healthcare provider can discuss a more complete list of pregnenolone side effects with you.)

Pregnenolone Side Effects to Report

Little is known about the possible side effects of pregnenolone. Theoretically, it might cause side effects associated with other hormones (since the body uses pregnenolone to make other hormones, such as estrogen, progesterone, and testosterone). It should be stressed that these potential side effects of pregnenolone are merely theoretical; they have not necessarily been linked to pregnenolone use in humans.
Although some of these side effects do not seem to be serious, they can signal a hormonal imbalance that could lead to more serious problems. These potential pregnenolone side effects that should be reported to your healthcare provider include but are not limited to:
  • Insomnia
  • Irritability
  • Menstrual changes
  • Acne
  • Headaches
  • Facial hair growth
  • Hair loss
  • An irregular heart rhythm (arrhythmia)
  • Anger
  • Anxiety
  • Negative mood changes
  • Seizures
  • Signs of an allergic reaction, such as:
    • Rash
    • Hives
    • Itching
    • Swelling of the mouth or throat
    • Wheezing
    • Difficulty breathing.
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