Pregnenolone Side Effects

Although pregnenolone is a "natural" product, it is not necessarily free of side effects. Pregnenolone can cause problems, such as insomnia, headaches, and hair loss. Side effects of this hormone may not seem serious, but they can be a sign of a hormonal imbalance that could lead to more serious problems. Therefore, if you experience any side effects of pregnenolone, make sure to contact your healthcare provider.

 

Side Effects of Pregnenolone: An Overview

As with any medication or supplement, pregnenolone can cause side effects. People often assume that natural products are always free of side effects, especially dangerous side effects. However, this is simply not the case. It should be assumed that any supplement potent enough for medicinal use is capable of causing side effects.
 
(This article covers many, but not all, of the possible side effects with pregnenolone. Your healthcare provider can discuss a more complete list of pregnenolone side effects with you.)
 

Pregnenolone Side Effects to Report

There are a number of potential side effects with pregnenolone that you should report to your healthcare provider. Although some of these side effects do not seem to be serious, they can signal a hormonal imbalance that could lead to more serious problems. These side effects that should be reported to your healthcare provider include, but are not limited to:
 
  • Insomnia
  • Irritability
  • Menstrual changes
  • Acne
  • Headaches
  • Facial hair growth
  • Hair loss
  • An irregular heart rhythm (arrhythmia)
  • Anger
  • Anxiety
  • Negative mood changes
  • Seizures
  • Signs of an allergic reaction, such as a rash, hives, itching, swelling of the mouth or throat, wheezing, or difficulty breathing.
     
(Pregnenolone Side Effects Continued: Page 2)
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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;