Clinical Effects

The effectiveness of Osphena has been evaluated in clinical studies. In these studies, postmenopausal women who had vaginal atrophy (thinning and inflammation of the vaginal walls) due to menopause were given either Osphena or a placebo (a "sugar pill" with no active ingredients). Women who reported painful sexual intercourse as their most bothersome symptom had an improvement in the amount of pain they experienced during sex when given Osphena. 

When and How to Take It

Some general considerations to keep in mind during treatment with Osphena include the following:
  • This medication comes in tablet form. It is taken by mouth once a day.
  • You should take Osphena with food.
  • You can take Osphena any time of day. Try to take your dose at about the same time each day, however, to keep an even level of the medication in your blood.
  • For the medication to work properly, it must be taken as prescribed.

Dosing Information

There is only one standard recommended dose of Osphena, regardless of your age or weight. As is always the case, do not adjust your dosage unless your healthcare provider specifically tells you to do so.
(Click Osphena Dosage for more information.)

Side Effects of Osphena

Just like any medicine, Osphena can cause side effects. However, not everyone who uses the drug will experience problems. Most women tolerate it quite well.
If reactions do occur, in most cases, they are minor and either require no treatment or are treated easily by you or your healthcare provider. Serious side effects are less common.
Common side effects of Osphena include but are not limited to:
  • Hot flushes
  • Vaginal discharge
  • Muscle spasms.
(Click Osphena Side Effects to learn more, including potentially serious side effects you should report immediately to your healthcare provider.)
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Osphena Medication Information

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