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Ogen Drug Interactions
If you combine grapefruit juice, rifamycin antibiotics, or St. John's wort with Ogen, drug interactions could occur. Taking these products together may affect the levels of Ogen in your body, which can increase your risk of developing side effects or reduce the effectiveness of Ogen. Drug interactions may also occur if Ogen is taken with certain antibiotics, seizure medications, or thyroid replacement medications.
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Ogen® (estropipate) can potentially interact with various other medications and substances. Some of the products that may lead to Ogen drug interactions include:
- Barbiturates, such as:
- Amobarbital (Amytal®)
- Butalbital (Fioricet®, Fiorinal®)
- Pentobarbital (Nembutal®)
- Phenobarbital (Luminal®)
- Secobarbital (Seconal®)
- Certain antifungal medications or antibiotics, such as:
- Clarithromycin (Biaxin®)
- Erythromycin (Ery-Tab®)
- Isoniazid (Nydrazid®)
- Itraconazole (Sporanox®)
- Ketoconazole (Nizoral®)
- Miconazole
- Telithromycin (Ketek®)
- Certain seizure medications, such as:
- Carbamazepine (Carbatrol®, Epitol®, Equetro™, Tegretol®)
- Oxcarbazepine (Trileptal®)
- Phenytoin (Dilantin®, Phenytek®)
- Cyclosporine (Gengraf®, Neoral®, Sandimmune®)
- Grapefruit juice
- Protease inhibitor human immunodeficiency virus (HIV) medications, such as:
- Amprenavir (Agenerase®)
- Atazanavir (Reyataz®)
- Fosamprenavir (Lexiva®)
- Indinavir (Crixivan®)
- Nelfinavir (Viracept®)
- Ritonavir (Norvir®)
- Rifamycin antibiotics, such as rifabutin (Mycobutin®), rifampin (Rifadin®), and rifapentine (Priftin®)
- St. John's wort (Hypericum perforatum), an herbal supplement
- Thyroid replacement medications, such as:
- Liothyronine (Cytomel®)
- Liotrix (Thyrolar®)
- Levothyroxine (Levothroid®, Levoxyl®, Synthroid®, Tirosint®, Unithroid®)
- Thyroid (Armor® Thyroid, Nature-Throid®).
Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD



