Specific Information on Prescribing and Taking Ogen

Ogen Dosing for Low Estrogen in Younger Women

The recommended starting Ogen dose for estrogen replacement in younger women who have low estrogen levels (due to a variety of causes) is 1.25 mg once daily. Your healthcare provider may increase your dose, as necessary, up to 7.5 mg once daily.
For this use, Ogen should be given cyclically (usually three weeks on, followed by 8 to 10 days off). This will help mimic the natural hormonal changes that occur with the menstrual cycle and will usually cause regular monthly periods.

A Note About Ogen Strengths

Ogen tablets come in the following strengths:
  • Ogen 0.625 mg (which contains 0.75 mg estropipate per tablet)
  • Ogen 1.25 mg (which contains 1.5 mg per estropipate per tablet)
  • Ogen 2.5 mg (which contains 3 mg of estropipate per tablet).
The strengths of Ogen can be a little confusing. The "official" strength is calculated in terms of sodium estrone sulfate, even though the tablets contain slightly more estropipate (also known as piperazine estrone sulfate). You may find that your pharmacy uses other ways to describe the strength. Just remember that Ogen (and its generic versions) only comes in three strengths. Ogen 0.625 is exactly the same as Ogen 0.75.

General Information on Dosing With Ogen

Considerations for people using Ogen include the following:
  • The medication comes in tablet form. It is taken by mouth once a day.
  • You can take Ogen with or without food. If the drug bothers your stomach, try taking it with food, since some women find estrogens to be irritating to the stomach.
  • Ogen is usually taken cyclically, with periodic breaks every once in a while, to allow for period-like bleeding. Your healthcare provider will help you decide exactly how to take the medication.
  • It does not matter what time of day you take Ogen, although it is best to take it at the same time each day.
  • The tablets may be broken in half, if necessary, to achieve the proper dosage.
  • For the medication to work properly, it must be taken as prescribed.
  • If you are unsure about anything related to your Ogen dosage, please talk to your doctor, nurse, or pharmacist.
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