Menopause Channel
Topics & Medications
Quicklinks
Related Channels
Menest
Menest is approved as a type of hormone replacement therapy. It is licensed for treating menopausal symptoms, reducing the symptoms of certain cancers, and treating hormonal deficiency in younger women whose ovaries do not produce enough estrogen. The drug comes in tablet form and is available in several strengths. Potential side effects include nausea, abdominal pain, and vaginal bleeding.
Interested in a Discount on Menest?
Enter your email address to see if eMedTV's free DiscountRx service has a program that could help you save on your prescription(s).
Thank you!
Thank you for your interest in DiscountRx from eMedTV. An email has been sent to the address you provided. Please follow the link within that email to see what offers may be available.
Menest® (esterified estrogens) is a prescription hormone replacement medication. Although it is most often used as a hormone replacement for menopausal women, it is approved for several different uses. Approved uses include:
- Treating menopausal symptoms, such as hot flashes and vaginal dryness
- Replacing hormones in younger women whose ovaries do not produce enough estrogen, or who have had their ovaries removed
- Reducing the symptoms of certain cancers (in both men and women) that have spread throughout the body.
(Click Menest Uses for more information, including possible off-label uses.)
Menest tablets are made by Monarch Pharmaceuticals, Inc., a division of King Pharmaceuticals, Inc.
Menest contains a mixture of different estrogens, which are derived from plant sources. It helps to relieve menopausal symptoms by replacing the estrogen that the ovaries no longer produce. Because estrogen helps keep the bones strong, the decrease during menopause causes a significant weakening of the bones, often resulting in osteoporosis. Menest can help prevent these menopause-related bone changes.
Very high doses of Menest can work to relieve the symptoms of certain cancers, including breast and prostate cancer. For prostate cancer, high doses of the estrogens in the medication work by suppressing testosterone and other male hormones that "feed" prostate cancer.
It is not entirely clear how high doses of Menest work for breast cancer, as estrogen usually stimulates cancer cell growth. This drug will not cure these types of cancers and should only be used to relieve symptoms when other treatments have failed to treat the disease adequately.
Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD