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Menest Drug Interactions
If you combine grapefruit juice, rifamycin antibiotics, or certain seizure medications with Menest, drug interactions may occur. These products, as well as other medications, can affect the level of Menest in your blood. These Menest interactions could increase your risk of developing side effects or decrease the effectiveness of the estrogen medicine.
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Menest® (esterified estrogens) can potentially interact with various other medications. While some of these interactions can be serious, some are rather minor. Some of the medicines that may lead to Menest interactions include:
- Barbiturates, including (but not limited to):
- Butalbital (Fioricet®, Fiorinal®)
- Pentobarbital (Nembutal®)
- Phenobarbital (Luminal®)
- Secobarbital (Seconal®)
- Certain antifungal medications or antibiotics, such as:
- Clarithromycin (Biaxin®)
- Erythromycin (Ery-Tab®)
- Isoniazid (Nydrazid®)
- Itraconazole (Sporanox®)
- Ketoconazole (Nizoral®)
- Miconazole
- Telithromycin (Ketek®)
- Certain seizure medications, such as:
- Carbamazepine (Carbatrol®, Epitol®, Equetro™, Tegretol®)
- Oxcarbazepine (Trileptal®)
- Phenytoin (Dilantin®, Phenytek®)
- Cyclosporine (Gengraf®, Neoral®, Sandimmune®)
- Grapefruit juice
- Hypothyroidism (underactive thyroid) medications, including:
- Liothyronine (Cytomel®)
- Liotrix (Thyrolar®)
- Levothyroxine (Levothroid®, Levoxyl®, Synthroid®, Tirosint®, Unithroid®)
- Thyroid (Armor® Thyroid, Nature-Throid®)
- Protease inhibitor HIV medications, such as:
- Amprenavir (Agenerase®)
- Atazanavir (Reyataz®)
- Fosamprenavir (Lexiva®)
- Indinavir (Crixivan®)
- Nelfinavir (Viracept®)
- Ritonavir (Norvir®)
- Rifamycin antibiotics, including rifabutin (Mycobutin®), rifampin (Rifadin®), and rifapentine (Priftin®)
- St. John's wort (Hypericum perforatum).
Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD