Menopause Home > Vagifem Warnings and Precautions
To help ensure a safe, effective treatment process with Vagifem, warnings and precautions should be reviewed with your healthcare provider. This medication is not suitable for everyone, and you may not be able to safely use it if you have cancer, high blood pressure, or heart disease. Vagifem warnings and precautions also apply to women who are pregnant or breastfeeding.
Vagifem: What Should I Tell My Healthcare Provider?Talk with your healthcare provider prior to using Vagifem® (estradiol vaginal tablets) if you have:
- Cancer (or if you have had cancer in the past)
- Unexplained vaginal bleeding
- High blood pressure (hypertension)
- High cholesterol
- A history of blood clots
- A history of heart attack or stroke
- Heart disease
- Liver disease, such as liver failure, cirrhosis, hepatitis, or liver tumors
- Kidney disease, including kidney failure (renal failure)
- Yellowing of the whites of the eyes or skin (jaundice) during a prior pregnancy or estrogen use
- High triglycerides
- Gallbladder disease
- Congestive heart failure (CHF)
- Uterine fibroids
- Any allergies, including allergies to drugs, foods, preservatives, or dyes.
Also, let your healthcare provider know if you:
- Are pregnant or thinking of becoming pregnant
- Are breastfeeding
- Have an upcoming surgery
- Smoke cigarettes.
Make sure to tell your healthcare provider about any other medicines you are taking, including prescription and non-prescription medicines, vitamins, and herbal supplements.