Menopause Home > More Info on Interactions With Vagifem

Rifamycin Antibiotics
Rifamycin antibiotics may cause your liver to metabolize the hormones in Vagifem too quickly, possibly leading to low levels of Vagifem in the body. Because Vagifem acts directly on the vaginal tissues, this interaction is probably not significant.
 
Some Seizure Medications
Some seizure medications may cause your liver to metabolize the hormones in Vagifem too quickly, possibly leading to low levels of Vagifem in the body. Because Vagifem acts directly on the vaginal tissues, this interaction is probably not significant.
 
St. John's Wort
St. John's wort (a commonly used herbal supplement) may cause your liver to metabolize the hormones in Vagifem too quickly, possibly leading to low levels of Vagifem in the body. Because Vagifem acts directly on the vaginal tissues, this interaction is probably not significant.
 
Thyroid Medications
If you take medications for an underactive thyroid (hypothyroidism) with Vagifem, your healthcare provider may need to increase the dose of your thyroid medication. Your healthcare provider should monitor you and make any necessary dosing adjustments.
 

Final Thoughts on Vagifem Drug Interactions

It is possible that not all Vagifem drug interactions were discussed in this article. Therefore, you should talk with your pharmacist or healthcare provider about the specific drug interactions that may apply to you.
 
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
List of references (click here):
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