Menopause Home > Prempro Warnings and Precautions
Before using Prempro, warnings and precautions for the medication should be reviewed with your healthcare provider. For example, make sure your healthcare provider is aware of any existing medical conditions you have, such as heart disease, diabetes, or kidney disease. Prempro warnings and precautions also include knowing that the drug may increase your risk of developing breast cancer, gallbladder disease, or dementia.
Prempro: What Should I Tell My Healthcare Provider?You should talk with your healthcare provider prior to using Prempro™ (conjugated estrogens/medroxyprogesterone) if you have:
- A history of blood clots
- Cancer (or if you have had cancer in the past)
- A history of heart attack or stroke
- Heart disease
- High blood pressure (hypertension)
- High cholesterol or high triglycerides
- Liver disease, such as liver failure, cirrhosis, hepatitis, or liver tumors
- Systemic lupus erythematosus (SLE or lupus)
- Kidney disease, including kidney failure (renal failure)
- Congestive heart failure (CHF)
- Yellowing of the whites of the eyes or skin (jaundice) during a prior pregnancy or estrogen use
- Gallbladder disease
- An underactive thyroid (hypothyroidism)
- Unexplained vaginal bleeding
- Any allergies, including allergies to drugs, foods, preservatives, or dyes.
Also, let your healthcare provider know if you:
- Have an upcoming surgery
- Smoke cigarettes
- Are pregnant or thinking of becoming pregnant
- Are breastfeeding.
Make sure to tell your healthcare provider about any other medicines you are taking, including prescription and non-prescription medicines, vitamins, and herbal supplements.