Menopause Home > More Info on Indications for Prempro

Prempro Uses for Osteoporosis

Because estrogen helps keep the bones strong, the decrease in estrogen during menopause causes a significant weakening of the bones, often resulting in osteoporosis. By providing estrogen, Prempro can help prevent these menopause-related bone changes. However, the drug is not risk-free, and it should only be used in women who cannot use other, non-hormonal medications for osteoporosis prevention and who have a significant risk for osteoporosis.

Prempro Uses in Children and Teens

Prempro is not approved for use in children for any use.

Off-Label Prempro Uses

On occasion, your healthcare provider may recommend Prempro for something other than the conditions discussed in this article. This is called an "off-label" use. At one point, Prempro (like other hormone therapies) was used off-label for preventing heart disease and forms of dementia (such as with Alzheimer's disease), but these are no longer considered legitimate off-label uses.
Sometimes hormones are used to promote youthfulness. Again, this is not generally accepted as a legitimate off-label Prempro use.
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
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