Menopause Home > Other Indications for Premarin
Premarin Use for Osteoporosis
Because estrogen helps to keep the bones strong, the decrease in estrogen during menopause causes a significant weakening of the bones, often resulting in osteoporosis. By providing estrogen, Premarin can help prevent these menopause-related bone changes. However, Premarin is not risk-free, and it should only be used in women who cannot use other, non-hormonal medications for osteoporosis prevention.
Premarin Use in Younger Women
Sometimes, younger women do not produce enough estrogen, for a variety of reasons. In some cases, the ovaries simply stop working too soon, for unknown reasons. In other instances, certain medications (such as chemotherapy) have affected the ability of the ovaries to function properly. Some women have had their ovaries surgically removed. Or, perhaps, the ovaries never started working properly in the first place (which results in delayed or absent puberty). In all of these situations, Premarin can be used as a substitute for the estrogen that the ovaries cannot produce.
Premarin Use for Cancer
Very high doses of Premarin can work to relieve the symptoms of certain cancers, including breast and prostate cancer. For prostate cancer, high doses of the estrogens in Premarin work by suppressing testosterone and other male hormones that "feed" prostate cancer. It is not entirely clear how high doses of Premarin work for breast cancer, as estrogen typically stimulates breast cancer cell growth. Premarin will not cure these types of cancers and should only be used to relieve symptoms when other treatments have failed to treat the cancer adequately. This is known as "palliative" cancer therapy.