Menopause Home > Premarin Vaginal Cream and Pregnancy
Premarin Vaginal Cream (conjugated estrogens vaginal cream) is considered a pregnancy Category X medication, which means it should not be used during pregnancy. Premarin Vaginal Cream may cause problems during pregnancy, and there is no legitimate medical reason for pregnant women to use this medication. If you are using Premarin Vaginal Cream and pregnancy occurs, contact your healthcare provider.
Premarin Vaginal Cream and Pregnancy: An OverviewPremarin® Vaginal Cream (conjugated estrogens vaginal cream) is a prescription estrogen medication used to treat vaginal dryness and other symptoms due to menopause. It is not, however, approved for use in pregnant women. There is no accepted medical reason for pregnant women to use Premarin Vaginal Cream.
Premarin Vaginal Cream and Pregnancy Category XAlmost all sources consider Premarin Vaginal Cream a pregnancy Category X medication, although this terminology is not used in the prescribing information for the cream -- which is common in older medications such as these.
The U.S. Food and Drug Administration (FDA) uses a category system to classify the possible risks to a fetus when a specific medicine is taken during pregnancy. Pregnancy Category X is given to medications that should not be used during pregnancy, usually due to serious problems that could occur, such as birth defects or miscarriages.
Although Premarin Vaginal Cream is a Category X medication, it does not appear to increase the risk of birth defects or other problems. However, because the risks are not fully understood, and because there is no accepted, legitimate medical reason for pregnant women to use Premarin Vaginal Cream, it should not be used during pregnancy.