Menopause Home > Ogen

Ogen is a hormone replacement medication that is often used for treating menopausal symptoms. It is also approved for preventing osteoporosis in postmenopausal women and replacing hormones in younger women whose ovaries do not produce enough estrogen. The medication comes in tablet form and is available by prescription only. While most women tolerate this drug well, potential side effects include nausea, headaches, and vaginal bleeding.

What Is Ogen?

Ogen® (estropipate) is a prescription hormone replacement medication. It is approved for the following uses:
  • Treating menopausal symptoms, such as hot flashes, night sweats, or vaginal dryness
  • Preventing osteoporosis in postmenopausal women
  • Replacing hormones in younger women whose ovaries do not produce enough estrogen or who have had their ovaries removed.
This article refers to Ogen tablets. The medicine also comes as a vaginal cream (see Ogen Vaginal Cream for more information). The vaginal cream is approved only for the vaginal symptoms of menopause.
(Click Ogen Uses for more information, including possible off-label uses.)

Who Makes It?

Brand-name Ogen tablets are made by Pfizer, Inc. Generic versions are made by several different manufacturers.

How Does Ogen Work?

Ogen contains estropipate, an estrogen medication. It helps relieve menopausal symptoms by replacing estrogen that the ovaries no longer produce. Because estrogen helps keep the bones strong, the decrease in estrogen during menopause causes a significant weakening of the bones, often resulting in osteoporosis. By providing estrogen, the medication can help prevent these menopause-related bone changes.
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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