Menopause Home > Ogen Dosage

The recommended Ogen dosage for the prevention of osteoporosis in postmenopausal women is 0.625 mg once daily, taken cyclically. For most women, the recommended starting dose for treating menopausal symptoms is also 0.625 mg once daily. The usual starting Ogen dose for estrogen replacement in younger women with low estrogen levels is 1.25 mg once daily. Your healthcare provider can increase these dosages as needed.

Ogen Dosage: An Introduction

The dose of Ogen® (estropipate) your healthcare provider recommends will vary, depending on a number of factors, including:
  • The medical condition being treated
  • How you respond to Ogen
  • Whether you have had a hysterectomy
  • Other medical conditions you may have.
As always, do not adjust your dose unless your healthcare provider specifically instructs you to do so.

Ogen Dosing for Osteoporosis Prevention

For preventing osteoporosis in postmenopausal women, the recommended dose is Ogen 0.625 mg once daily, taken cyclically (25 days on, 6 days off).

Ogen Dosing for Menopause

When using Ogen for menopausal symptoms, it is typically recommended that this medication be taken at the lowest effective dose for the shortest possible time. However, the most effective dose (and how long it should be taken) can vary considerably from one woman to the next. For most women, the recommended starting dose is Ogen 0.625 mg once daily. If necessary, your healthcare provider may increase your dose up to Ogen 5 mg once daily.
Ogen is approved for cyclic use, such as three weeks on and one week off. Taking it cyclically can help promote regular, menstrual-like bleeding and decrease breakthrough bleeding, especially in younger women. Some healthcare providers may also recommend continuous use of Ogen (taking it every day without any breaks). Taking it continuously can result in a complete absence of bleeding, especially in older women, a side effect that many women desire.
If you still have a uterus, you must take Ogen with a progestin hormone in order to reduce the risk of precancerous and cancerous uterine changes. The progestin can be taken every day or for just a certain part of the cycle (often the last half of each cycle). If you have had a hysterectomy, you do not have to take progesterone along with Ogen.
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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