Menopause Home > Understanding Mimvey's Effects and Treatment Tips

How Does Mimvey Work?

During and after menopause, women experience a drop in estrogen levels and a shift in the balance of estrogens that the body produces. Before menopause, the main source of estrogen is produced by the ovaries, and the main type of estrogen produced is known as estradiol.
After menopause, the main source of estrogen is androstenedione, which is produced by the adrenal gland and is converted into an estrogen known as estrone. Menopausal symptoms and changes result from the decrease in estrogen and the shift from estradiol to estrone.
Mimvey contains estradiol along with a progestin hormone (norethindrone). It helps relieve menopausal symptoms by replacing the estrogen that the ovaries no longer produce. Because estrogen helps keep the bones strong, the decrease during menopause causes a significant weakening of the bones, often resulting in osteoporosis. By providing estrogen, Mimvey can help prevent these menopause-related bone changes.
Norethindrone is added to Mimvey because giving estrogens without a progestin to postmenopausal women can increase the risk of cancer of the lining of the uterus. Norethindrone, which is a progestin, decreases this risk. Of course, this applies only to women who still have a uterus (who have not had a hysterectomy). For women without a uterus, the norethindrone component is usually considered unnecessary.

When and How to Use Mimvey

Some general considerations to keep in mind during treatment with Mimvey include the following:
  • The medication comes in tablet form. It is taken by mouth once a day, every day.
  • You can take it with or without food. If Mimvey bothers your stomach, try taking it with food.
  • It does not matter what time of day you take Mimvey, although it is best to take it at the same time each day.
  • For the medication to work properly, it must be taken as prescribed.
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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