If you have hot flashes caused by menopause, your healthcare provider may recommend a product called BrisdelleTM (paroxetine mesylate capsules). Although this prescription product can be an effective medication for many women, it's important to review the safety information before starting treatment to help minimize your risk for problems. In particular, let your healthcare provider know if you have glaucoma, a history of breast cancer, or are taking any other medicines.
Brisdelle comes in the form of a capsule that is taken once daily at bedtime. Side effects are possible and include headaches, nausea, and fatigue.
Brisdelle is the first non-hormonal drug approved to treat hot flashes in women going through menopause.
(For more information on this medication, click Brisdelle. This Web article discusses various topics related to this medicine, such as how it works, possible safety concerns, what to do in cases of overdose, and more.)
Food and Drug Administration. FDA approves the first non-hormonal treatment for hot flashes associated with menopause (July 2, 2013). FDA Web site. Available at: http://www.fda.gov/newsevents/newsroom/pressannouncements/ucm359030.htm. Accessed August 23, 2013.
Imai A, Matsunami K, Takagi H, Ichigo S. New generational nonhormonal management for hot flashes. Gynecol Endocrinol 2013;29(1):63-66.
Shams T, Firwana B, Habib F, Alshahrani A, AlNouh B, Murad MH, Ferwana M. SSRIs for hot flashes: a systemic review and meta-analysis of randomized trials. J Gen Intern Med 2013 Jul 26. [Epub ahead of print].
Food and Drug Administration, Center for Drug Evaluation and Research. Electronic orange book: approved drug products with therapeutic equivalence evaluations. FDA Web site. Available at: http://www.fda.gov/cder/ob/. Accessed August 23, 2013.
Briggs GG, Freeman RK, Yaffe SJ. Drugs in Pregnancy and Lactation. 8th ed. Philadelphia (PA): Lippincott Williams & Wilkins;2008.
National Library of Medicine (US). Drugs and Lactation Database (LactMED). NLM Web site. Available at: http://toxnet.nlm.nih.gov/cgi-bin/sis/htmlgen?LACT. Accessed August 23, 2013.
National Library of Medicine (US). Hazardous Substances Data Bank (HSDB). NLM Web site. Available at: http://toxnet.nlm.nih.gov/cgi-bin/sis/htmlgen?HSDB. Accessed August 23, 2013.
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