Menopause Home > Menest Side Effects

Headaches, breast tenderness, and fluid retention are some of the common side effects that have been reported with estrogen medications such as Menest. Side effects of the drug are minor in most cases and typically do not require medical attention. However, you should contact your healthcare provider immediately if you develop any serious side effects of Menest, such as chest pain, vision changes, and allergic reactions.

An Introduction to Menest Side Effects

As with any medicine, Menest® (esterified estrogens) can cause side effects. However, not everyone who takes the drug will experience side effects. In fact, most people tolerate it quite well. If side effects do occur, in most cases, they are minor and either require no treatment or can easily be treated by you or your healthcare provider.
(This article covers many, but not all, of the possible side effects with Menest. Your healthcare provider can discuss a more complete list of Menest side effects with you.)

Common Side Effects of Menest

Common side effects of estrogen medications, such as Menest, include (but are not limited to):
  • Nausea and vomiting
  • Hair loss
  • High blood pressure
  • High blood sugar (hyperglycemia)
  • Headaches
  • Breast tenderness
  • Irregular vaginal bleeding or spotting
  • Abdominal (stomach) cramps or bloating
  • Fluid retention
  • Enlargement of benign tumors of the uterus (uterine fibroids)
  • Vaginal yeast infections.
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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