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Specific Jinteli Precautions and Warnings

Some warnings and precautions to be aware of prior to taking this medication include the following:
  • Estrogen/progestin drugs, like Jinteli, may increase the risk for breast cancer. Proper screening and monitoring (as determined by your healthcare provider), such as yearly mammograms and monthly self-breast exams, are recommended.
  • Your healthcare provider should make sure you are appropriately treated for any risk factors for heart disease, strokes, or blood clots before you take Jinteli. Risk factors include:
  • Let your healthcare provider know if you have abnormal vaginal bleeding (such as heavy bleeding or bleeding between periods) while taking Jinteli, as this may be a sign of precancerous or cancerous changes in the uterus. Your healthcare provider can perform the necessary tests to rule out cancer.
  • When possible, Jinteli should be stopped four to six weeks before many surgeries to help prevent blood clots.
  • Estrogen-containing drugs, such as Jinteli, seem to increase the risk for dementia. In no case should Jinteli be used to prevent or treat dementia, as it is not effective for this use.
  • Jinteli should be used with caution in people who have low calcium levels in the blood (known medically as hypocalcemia).
  • Women who take estrogen-containing medications like Jinteli have an increased risk for gallbladder disease.
  • Let your healthcare provider know right away if you notice any vision changes. This can signal a blood clot in the retina, a possible side effect of Jinteli.
  • If you have had jaundice (yellowing of the whites of the eyes or skin) due to estrogens or pregnancy in the past, Jinteli could cause similar problems to recur. If this happens, your healthcare provider will probably advise you to stop taking the drug.
  • If you have an underactive thyroid (hypothyroidism), Jinteli may increase your body's requirement for thyroid hormones. Your healthcare provider should monitor you and adjust the dose of your thyroid medications as necessary.
  • Jinteli can cause fluid retention, which may cause problems for people with congestive heart failure (CHF) or kidney problems.
  • It is not clear if Jinteli increases the risk for ovarian cancer. Some studies have shown an increased risk, while others have not.
  • This medication can make endometriosis symptoms worse.
  • The hormones in Jinteli pass through breast milk. Therefore, if you are breastfeeding or plan to start, discuss this with your healthcare provider prior to taking the drug (see Femhrt and Breastfeeding).
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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