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Interactions With Estropipate Vaginal Cream Explained
The following sections explain in detail the potentially negative interactions that can occur when estropipate vaginal cream is combined with any of the drugs listed above.
Certain Antibiotics or Antifungals
Some antibiotic or antifungal medications may decrease your body's ability to metabolize estropipate vaginal cream, possibly leading to higher-than-normal levels of the cream in the body. This may increase the risk of side effects of estropipate vaginal cream. Check with your healthcare provider before combining estropipate vaginal cream with certain antibiotics or antifungals.
Cyclosporine (Gengraf, Neoral, Sandimmune)
Estropipate vaginal cream may increase the level of cyclosporine in your blood, which could increase the chance of cyclosporine side effects. Talk with your healthcare provider before taking these medications together. You may need a lower cyclosporine dose, or you may need to switch to one of the many alternatives to estropipate vaginal cream.
Protease inhibitors may decrease your body's ability to metabolize estropipate vaginal cream, possibly leading to high levels of estropipate vaginal cream in the body. This may increase the risk of side effects. Check with your healthcare provider before combining the estrogen medication with a protease inhibitor.
If you take medications for an underactive thyroid (hypothyroidism) with estropipate vaginal cream, your healthcare provider may need to increase the dose of your thyroid medication. Your healthcare provider should monitor you and make any necessary dosing adjustments.
It is possible that not every drug interaction with estropipate vaginal cream was discussed in this article. Therefore, you should talk with your pharmacist or healthcare provider about the specific drug interactions that may apply to you.