Menopause Home > Estring and Pregnancy

Estring is considered a pregnancy Category X medication, which means that it should not be used intentionally during pregnancy. Estring does not appear to increase the risk of birth defects, but the full risks are not known. Also, there is no legitimate medical reason for a woman to use this medication while pregnant. If you are using Estring and pregnancy occurs, contact your healthcare provider.

Can I Use Estring During Pregnancy?

Estring® (estradiol vaginal ring) is a prescription estrogen medication used to treat menopause symptoms. The drug should not be used by pregnant women.

Estring and Pregnancy Category X

The U.S. Food and Drug Administration (FDA) uses a category system to classify the possible risks to a fetus when a specific medicine is taken during pregnancy. Pregnancy Category X is the most serious rating and is given to medications that should not ever be used during pregnancy, usually due to serious problems that could occur, such as birth defects or miscarriages.
Despite that fact that Estring is considered a pregnancy Category X medication, the hormone in Estring (estradiol) does not appear to increase the risk of birth defects or other problems. In fact, estradiol is the predominant estrogen hormone produced naturally by pregnant women. However, because the risks are not fully understood, and because there is no accepted, legitimate medical reason for pregnant women to use Estring, it should not be used during pregnancy.
It is essential to understand that estrogen medications such as Estring are not effective for preventing miscarriages, even though they were used for such uses many years ago.

Estring and Pregnancy: Final Thoughts

Estring should not be used by pregnant women. If you used the drug for a while before realizing you were pregnant, it will probably not cause any problems, although you should discuss this with your healthcare provider. If you think you may be pregnant, you should contact your healthcare provider for further instructions.
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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