Menopause Home > Enjuvia Side Effects

Most women tolerate Enjuvia well and do not experience any major side effects. Enjuvia, however, can cause problems, such as headaches, nausea, and breast pain. These types of side effects are typically minor and easily treated. However, you should contact your healthcare provider right away if you develop more serious Enjuvia side effects, such as chest pain, vision changes, or signs of an allergic reaction.

An Introduction to Enjuvia Side Effects

As with any medicine, Enjuvia® (conjugated estrogens) can cause side effects. However, not everyone who takes Enjuvia will experience side effects. In fact, most people tolerate it quite well. If side effects do occur, in most cases, they are minor and either require no treatment or are easily treated by you or your healthcare provider.
(This article covers many, but not all, of the possible side effects with Enjuvia. Your healthcare provider can discuss a more complete list of Enjuvia side effects with you.)

Common Side Effects of Enjuvia

Enjuvia has been thoroughly studied in clinical trials. In these studies, the side effects that occurred in a group of people taking the drug were documented and then compared to the side effects that occurred in another group of people taking a placebo (a "sugar pill" that does not contain any active ingredients). As a result, it was possible to see what side effects occurred, how often they appeared, and how they compared to the group not taking the medicine.
In these studies, the most common Enjuvia side effects included:
  • Headaches -- in up to 25 percent of women
  • Pain -- up to 19 percent
  • Abdominal pain (stomach pain) -- up to 15 percent
  • Breast pain -- up to 14 percent
  • Nausea -- up to 12 percent.
Other common Enjuvia side effects, occurring in 5 to 10 percent of women included:
  • The flu or flu-like symptoms (such as fever or chills)
  • Gas
  • Dizziness
  • Unusual sensations, such as burning, tingling, or pricking
  • Bronchitis
  • A runny or stuffy nose
  • Sinus infections
  • Menstrual cramps
  • Vaginal irritation or infections.
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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