Menopause Home > Elestrin Side Effects

Nasal or throat irritation, irregular vaginal bleeding or spotting, and breast tenderness are the most common side effects reported with Elestrin. Side effects of the estrogen medication are typically mild and do not require medical attention in most cases. However, there are some potentially serious Elestrin side effects that may occur (such as chest pain, sudden vision loss, and migraines). These should be reported to a healthcare provider right away.

An Introduction to Elestrin Side Effects

As with any medicine, Elestrin™ (estradiol gel) can cause side effects. However, not everyone who uses the medication will experience side effects. In fact, most people tolerate it quite well. If side effects do occur, in most cases, they are minor and either require no treatment or can easily be treated by you or your healthcare provider.
 
(This article covers many, but not all, of the possible side effects with Elestrin. Your healthcare provider can discuss a more complete list of Elestrin side effects with you.)
 

Common Side Effects of Elestrin

Elestrin has been thoroughly studied in clinical trials. In these studies, the side effects that occurred in a group of people taking the drug were documented and then compared to the side effects that occurred in another group of people taking a placebo (in this case, a gel without the active ingredients). As a result, it was possible to see what side effects occurred, how often they appeared, and how they compared to the group not taking the medicine.
 
In these studies, the most common Elestrin side effects included:
 
  • Nasal or throat irritation symptoms (like the common cold) -- in up to 10.3 percent of women
  • Irregular vaginal bleeding or spotting -- up to 9.2 percent
  • Breast tenderness -- up to 7.7 percent.
     
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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