Menopause Home > Specific Info on Drugs That Interfere With Cenestin

Cenestin Interactions Explained

The following sections explain in detail the potentially negative interactions that can occur when Cenestin is combined with any of the drugs listed above.
 
Barbiturates
Barbiturates may cause your body to metabolize the hormones in Cenestin too quickly, leading to low levels of Cenestin in the body. Although this can make Cenestin less effective, it is not considered a dangerous or serious drug interaction.
 
Certain Seizure Medications
Some seizure medications may cause your body to metabolize the hormones in Cenestin too quickly, leading to low levels of Cenestin in the body. Although this can make Cenestin less effective, it is not a dangerous drug interaction.
 
Cyclosporine (Gengraf, Neoral, Sandimmune)
Cenestin may increase the level of cyclosporine in your blood, increasing the chance of side effects of cyclosporine. Talk with your healthcare provider before taking these medications together. You may need a lower cyclosporine dose, or you may need to switch to one of the many Cenestin alternatives.
 
Grapefruit Juice
Grapefruit juice may decrease the ability of your liver to metabolize Cenestin, leading to high levels of Cenestin in the body. This may increase the risk of Cenestin side effects.
 
Protease Inhibitors
Protease inhibitors may decrease the ability of your liver to metabolize Cenestin, leading to high levels of Cenestin in the body. This may increase the risk of Cenestin side effects. Check with your healthcare provider before combining Cenestin with a protease inhibitor.
 
Rifamycin Antibiotics
Rifamycin antibiotics may cause your body to metabolize the hormones in Cenestin too quickly, leading to low levels of Cenestin in the body. Although this can make Cenestin less effective, it is not a dangerous drug interaction.
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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