Black cohosh may increase the level of risperidone in your blood, increasing your risk of side effects of risperidone. Check with your healthcare provider before taking risperidone with black cohosh.
Tramadol (Rybix ODT, Ryzolt, Ultram, Ultram ER) or Tramadol and Acetaminophen (Ultracet)
It is thought that black cohosh may slow the breakdown of tramadol in your body, perhaps increasing your risk of tramadol side effects. It may be a good idea to avoid taking tramadol and black cohosh together.
Final Thoughts on Black Cohosh Drug Interactions
It is possible that not every drug interaction with black cohosh was discussed in this article. Therefore, you should talk with your pharmacist or healthcare provider about the black cohosh interactions that may apply to you.
Written by/reviewed by: Kristi Monson, PharmD;Arthur Schoenstadt, MD
Last reviewed by: KristiMonson, PharmD;
List of references (click here):
Jellin JM, editor. Pharmacist's Letter/Prescriber's Letter Natural Medicines Comprehensive Database Web site. Available at: http://naturaldatabase.com/. Accessed January 8, 2008.
National Center for Complimentary and Alternative Medicine. National Institutes of Health. Herbs at a glance: black cohosh (July 2005). NCCAM Web site. http://nccam.nih.gov/health/blackcohosh/. Accessed January 8, 2008.
Office of Dietary Supplements. National Center for Complimentary and Alternative Medicine. National Institutes of Health. Questions and answers about black cohosh and the symptoms of menopause (June 2006). NCCAM Web site. http://ods.od.nih.gov/factsheets/BlackCohosh.asp/. Accessed January 8, 2008.
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