Menopause Home > Ensuring Your Safety With Angeliq

Specific Precautions and Warnings for Angeliq

Some of the warnings and precautions to be aware of prior to using Angeliq include the following:
  • Angeliq contains drospirenone, a hormone that can increase the level of potassium in the blood. This is not usually a problem for most healthy women. It can be a problem if you take other medications that also increase potassium (see Angeliq Drug Interactions) or if you have kidney, liver, or adrenal problems.
  • Estrogen/progestin drugs (like Angeliq) may increase the risk of breast cancer. Proper screening and monitoring (as determined by your healthcare provider), such as yearly mammograms and monthly breast self-exams, are recommended.
  • Studies have also shown that estrogen plus progestin hormone replacement therapy (such as Angeliq) increases the risks of heart attacks, strokes, and blood clots in the legs and lungs. In no case should Angeliq be used to prevent heart disease (see Hormone Replacement Therapy and Heart Health for more information), as it is not effective for this use.
  • Your healthcare provider should make sure that you are appropriately treated for any risk factors for heart disease, strokes, or blood clots (such as high blood pressure, high cholesterol, diabetes, obesity, lupus, or smoking) before you take Angeliq.
  • Let your healthcare provider know if you have abnormal vaginal bleeding (such as very heavy bleeding or bleeding between periods) while taking Angeliq, as this may be a sign of precancerous or cancerous changes in the uterus. Your healthcare provider can perform the necessary tests to rule out cancer.
  • When possible, Angeliq should be stopped four to six weeks before many surgeries, in order to help prevent blood clots.
  • Estrogen-containing drugs (such as Angeliq) seem to increase the risk of dementia. In no case should Angeliq be used to prevent or treat dementia (it is not effective for this use).
  • Angeliq should be used with caution in people who have low calcium levels in the blood (known medically as hypocalcemia).
  • Women who take estrogen-containing medications like Angeliq have an increased risk for gallbladder disease.
  • Let your healthcare provider know right away if you notice any vision changes. This can signal a blood clot in the retina, a possible side effect of Angeliq.
  • Angeliq can cause high blood pressure (hypertension) or high triglycerides in some women. Your healthcare provider should monitor you for these problems.
  • If you have had jaundice (yellowing of the whites of the eyes or skin) due to estrogens or pregnancy in the past, it is possible that Angeliq will cause similar problems to recur. If this happens, your healthcare provider will probably advise you to stop taking Angeliq.
  • If you have an underactive thyroid (hypothyroidism), Angeliq may increase your body's requirement for thyroid hormones. Your healthcare provider should monitor you and adjust the dose of your thyroid medications as necessary.
  • Angeliq may worsen epilepsy, porphyria, asthma, diabetes, migraine headaches, lupus, and hepatic hemangiomas.
  • Angeliq can cause fluid retention. This can cause problems for people with congestive heart failure (CHF) or kidney problems.
  • It is not clear if Angeliq increases the risk of ovarian cancer. Some studies have shown an increased risk, while others have not.
  • Angeliq can make endometriosis symptoms worse.
  • Angeliq can interact with a number of different medications (see Angeliq Drug Interactions for more information).
  • Angeliq should not be used during pregnancy (see Angeliq and Pregnancy).
  • The hormones in Angeliq pass through breast milk. Therefore, if you are breastfeeding or plan to start breastfeeding, discuss this with your healthcare provider prior to taking the drug (see Angeliq and Breastfeeding).
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
List of references (click here):
Other Articles in This eMedTV Presentation

Topics & Medications


Related Channels

eMedTV Links
Copyright © 2006-2019 Clinaero, Inc.

eMedTV serves only as an informational resource. This site does not dispense medical advice or advice of any kind. Site users seeking medical advice about their specific situation should consult with their own physician. Click Terms of Use for more information.

This site complies with the HONcode standard for trustworthy health information:
verify here.