Menopause Home > More Info on Indications for Activella
Because estrogen helps keep the bones strong, the decrease in estrogen during menopause causes a significant weakening of the bones, often resulting in osteoporosis. By providing estrogen, Activella can help prevent these menopause-related bone changes. However, the drug is not risk-free and should only be used in women who cannot use other, non-hormonal medications for osteoporosis prevention and who are at significant risk for osteoporosis.
Activella is not approved for use in children or teens for any use.
On occasion, your healthcare provider may recommend Activella for something other than the conditions discussed in this article. This is called an "off-label" use. At one point, hormone replacement therapy (such as Activella) was used off-label for preventing heart disease and dementia, such as with Alzheimer's disease, but these are no longer considered legitimate off-label uses.
Sometimes hormones are used to promote youthfulness. Again, this is not generally accepted as a legitimate off-label Activella use.