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Drugs That Interfere With Femring
Femring Interactions Explained
The following sections explain in detail the potentially negative interactions that can occur when Femring is combined with any of the drugs listed above.
Barbiturate Medications
Barbiturates may cause your liver to metabolize the hormones in Femring more quickly than normal, which could lead to low levels of Femring in the body. Because Femring acts directly on the vaginal tissues, this interaction is probably not significant.
Certain Antibiotics or Antifungals
Some antibiotic or antifungal medications may decrease the ability of your liver to metabolize Femring, possible leading to higher-than-normal levels of Femring in the body. This may increase the risk of Femring side effects. Check with your healthcare provider before combining Femring with antibiotics or antifungals.
Cyclosporine (Gengraf, Neoral, Sandimmune)
Femring may increase the level of cyclosporine in your blood, possibly increasing the chance of side effects of cyclosporine. Talk with your healthcare provider before taking these medications together. You may need a lower cyclosporine dosage, or you may need to switch to one of the many Femring alternatives.
Protease Inhibitors
Protease inhibitors may decrease the ability of your liver to metabolize Femring, possibly leading to higher-than-normal levels of Femring in the body. This may increase the risk of Femring side effects. Check with your healthcare provider before combining Femring with a protease inhibitor.
Rifamycin Antibiotics
Rifamycin antibiotics may cause your liver to metabolize the hormones in Femring too quickly, possibly leading to low levels of Femring in the body. However, because Femring acts directly on the vaginal tissues, this interaction is probably not significant.
Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD