EstroGel Warnings and Precautions

Before taking EstroGel, make sure to talk to your healthcare provider about any existing medical conditions you have and any other medications you are taking, including vitamins. You may not be able to safely take EstroGel if you have certain health conditions, such as diabetes, asthma, or epilepsy, as EstroGel can make these conditions worse. Other EstroGel warnings and precautions include potential drug interactions and the safety of using the drug when pregnant or breastfeeding.

 

EstroGel: What Should I Tell My Healthcare Provider?

You should talk with your healthcare provider prior to using EstroGel® (estradiol gel) if you have:
 
  • Heart disease or heart problems of any kind
  • Cancer (or if you have had cancer in the past)
  • Had a heart attack or stroke
  • Had a blood clot
  • High blood pressure (hypertension)
  • Diabetes
  • Had yellowing of the whites of the eyes or skin (jaundice) during a prior pregnancy or estrogen use
  • Systemic lupus erythematosus (SLE, or lupus)
  • Asthma
  • Porphyria (a condition involving problems with certain enzymes in the body)
  • Seizures or epilepsy
  • Kidney disease, including kidney failure (renal failure)
  • Gallbladder disease
  • High cholesterol or high triglycerides
  • Migraines
  • Hepatic hemangioma (a kind of liver tumor)
  • Liver disease, such as liver failure, cirrhosis, hepatitis, or liver tumors
  • An underactive thyroid (hypothyroidism)
  • Endometriosis
  • Unexplained vaginal bleeding
  • Any allergies, including allergies to drugs, foods, preservatives, or dyes.
     
Also, let your healthcare provider know if you:
 
  • Have an upcoming surgery
  • Smoke cigarettes
  • Are pregnant or thinking of becoming pregnant
  • Are breastfeeding.
     
Make sure to tell your healthcare provider about any other medicines you are taking, including prescription and non-prescription medicines, vitamins, and herbal supplements.
 
(EstroGel Warnings and Precautions Continued: Page 2)
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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;