Serious Reactions to Estring

Serious Side Effects

Some side effects of estrogen medications are rare but are serious enough to mention. It is thought that Estring has a low risk of these serious problems, as it provides such a low dose of estrogen, compared to most other estrogen products. These include:
 
Because of the potentially serious nature of these side effects, there are a few symptoms you should watch out for and report to your healthcare provider immediately if they occur. These include but are not limited to:
 
  • Signs of a blood clot in the leg, such as:
 
    • Pain in the calf
    • Leg cramps
    • Leg or foot swelling
 
  • Signs of a blood clot in the lung, such as:
 
    • Shortness of breath
    • Sharp chest pain
    • Coughing up blood
 
 
    • Vision or speech changes
    • Weakness or numbness in an arm or leg
    • Severe headache
 
  • Signs of liver damage, such as:
 
    • Yellowing of the whites of the eyes or skin (jaundice)
    • Dark urine
    • Upper-right abdominal pain (stomach pain)
 
  • Migraines (or changes in your migraines, if you have had them before)
  • Breast lumps
  • Chest pain or heaviness, which may be signs of a heart attack
  • Sudden loss of vision or vision changes, which can be a sign of a blood clot in the eye
  • Heavy vaginal bleeding or unexpected vaginal bleeding
  • Signs of an allergic reaction, such as:
 
    • An unexplained rash
    • Hives
    • Itching
    • Unexplained swelling
    • Wheezing
    • Difficulty breathing or swallowing.
 
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