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Estrace
Estrace is an estrogen medication used to relieve several conditions related to menopause, such as treating hot flashes and vaginal dryness, and preventing osteoporosis in postmenopausal women. This prescription medication works by replacing the estrogen that the ovaries no longer produce. Estrace comes in tablet form and is generally taken once daily. Potential side effects include headaches, nausea, and breast pain.
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Estrace® (estradiol) is a prescription hormone replacement medication. It is approved for a number of uses, such as:
- Treating menopausal symptoms, such as hot flashes and vaginal dryness
- Preventing osteoporosis in postmenopausal women
- Replacing hormones in younger women whose ovaries do not produce enough estrogen (or who have had their ovaries removed)
- Reducing the symptoms of certain cancers (in both men and women) that have spread throughout the body.
This article refers to Estrace tablets. The medication also comes as a vaginal cream (see Estrace Vaginal Cream for more information). However, this is only approved for treating the vaginal symptoms of menopause.
(Click Estrace Uses for more information, including possible off-label uses.)
Estrace tablets are marketed by Warner Chilcott and are manufactured by Bristol-Myers Squibb Company or Barr Laboratories, Inc. Generic versions are made by several different manufacturers.
Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD



