Estrace Warnings and Precautions

There are several potential risks associated with Estrace. Warnings and precautions for this medication should be fully understood before starting treatment. For example, you may not be able to safely use Estrace if you have certain health conditions, such as heart disease, diabetes, or endometriosis. Estrace warnings and precautions also extend to women who are pregnant or breastfeeding.

Estrace Tablet Information

Estrace: What Should I Tell My Healthcare Provider?

You should talk with your healthcare provider prior to using Estrace^® (estradiol) if you have:

Had a heart attack or stroke
Heart disease
Had a blood clot
High blood pressure (hypertension)
High cholesterol
Unexplained vaginal bleeding
Cancer (or if you have had cancer in the past)
Diabetes
Had yellowing of the whites of the eyes or skin (jaundice) during a prior pregnancy or estrogen use
High cholesterol
Gallbladder disease
Liver disease, such as liver failure, cirrhosis, hepatitis, or liver tumors
Kidney disease, including kidney failure (renal failure)
Congestive heart failure (CHF)
An underactive thyroid (hypothyroidism)
Low calcium levels in the blood (hypocalcemia)
Endometriosis
Any allergies, including allergies to drugs, foods, preservatives, or dyes.

Also, let your healthcare provider know if you:

Have an upcoming surgery
Smoke cigarettes
Are pregnant or thinking of becoming pregnant
Are breastfeeding.

Make sure to tell your healthcare provider about any other medicines you are taking, including prescription and non-prescription medicines, vitamins, and herbal supplements.

(Estrace Warnings and Precautions Continued: Page 2)