Estrace Side Effects

Headaches, breast tenderness, and irregular vaginal bleeding or spotting are some of the common side effects of Estrace. Fortunately, reactions are typically minor and easily treated. Although most women tolerate Estrace well, serious problems can also occur. Notify your healthcare provider immediately if you develop chest pain, vision changes, or heavy vaginal bleeding.

An Introduction to Estrace Side Effects

Just like any medicine, Estrace® (estradiol) can cause side effects. However, not everyone who takes the drug will experience problems. In fact, most people tolerate it quite well. If side effects do occur, in most cases, they are minor and either require no treatment or are treated easily by you or your healthcare provider.
 
(This article covers many, but not all, of the possible side effects with Estrace. Your healthcare provider can discuss a more complete list with you.)
 

Common Side Effects of Estrace

Common side effects of estrogen medications such as Estrace include but are not limited to:
 
  • Headaches
  • Breast tenderness
  • Irregular vaginal bleeding or spotting
  • Abdominal (stomach) cramps or bloating
  • Nausea and vomiting
  • Hair loss
  • High blood pressure
  • High blood sugar (hyperglycemia)
  • Fluid retention
  • Enlargement of benign tumors of the uterus (uterine fibroids)
  • Vaginal yeast infections.
     

Serious Side Effects

Some side effects of estrogens are rare, but are serious enough to mention. These include:
 
Because of the possibility of these serious side effects with Estrace, there are a few symptoms that you should watch out for and immediately report to your healthcare provider. These include but are not limited to:
 
 
    • Vision or speech changes
    • Weakness or numbness in an arm or leg
    • Severe headache
 
  • Signs of a blood clot in the leg, such as:
 
    • Pain in the calf
    • Leg cramps
    • Leg or foot swelling
 
  • Signs of a blood clot in the lung, such as:
 
    • Shortness of breath
    • Sharp chest pain
    • Coughing up blood
 
  • Chest pain or heaviness, which may be signs of a heart attack
  • Sudden loss of vision or vision changes, which can be a sign of a blood clot in the eye
  • Signs of liver damage, such as:
 
    • Yellowing of the whites of the eyes or skin (jaundice)
    • Dark urine
    • Upper-right abdominal pain (stomach pain)
 
  • Migraines (or changes in your migraines, if you have had them before)
  • Breast lumps
  • Heavy vaginal bleeding or unexpected vaginal bleeding
  • Signs of an allergic reaction, including:
 
    • An unexplained rash
    • Hives
    • Itching
    • Unexplained swelling
    • Wheezing
    • Difficulty breathing or swallowing.
 
 
Men and Osteoporosis

Estrace Tablet Information

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