Estrace Side Effects

Headaches, breast tenderness, and irregular vaginal bleeding or spotting are some of the common side effects of Estrace. Side effects of this medication are typically minor and either require no treatment or are easily treated by you or your healthcare provider. Although most women tolerate Estrace well, serious side effects can also occur. Notify your healthcare provider immediately if you develop serious Estrace side effects, such as chest pain, vision changes, or heavy vaginal bleeding.

 

An Introduction to Estrace Side Effects

As with any medicine, Estrace® (estradiol) can cause side effects. However, not everyone who takes Estrace will experience side effects. In fact, most people tolerate it quite well. If side effects do occur, in most cases, they are minor and either require no treatment or are easily treated by you or your healthcare provider.
 
(This article covers many, but not all, of the possible side effects with Estrace. Your healthcare provider can discuss a more complete list of Estrace side effects with you.)
 

Common Side Effects of Estrace

Common side effects of estrogen medications (such as Estrace) include, but are not limited to:
 
  • Headaches
  • Breast tenderness
  • Irregular vaginal bleeding or spotting
  • Abdominal (stomach) cramps or bloating
  • Nausea and vomiting
  • Hair loss
  • High blood pressure
  • High blood sugar (hyperglycemia)
  • Fluid retention
  • Enlargement of benign tumors of the uterus (uterine fibroids)
  • Vaginal yeast infections.
     
(Estrace Side Effects Continued: Page 2)
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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;