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Estrace Vaginal Cream Drug Interactions

When certain medications, such as protease inhibitors or barbiturates, are used in combination with Estrace Vaginal Cream, drug interactions may occur. These medications could decrease the effectiveness of Estrace Vaginal Cream or increase your risk of developing side effects. Other medications that may cause Estrace Vaginal Cream interactions include rifamycin antibiotics, thyroid medicines, St. John's wort, and certain antifungals or antibiotics.

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An Introduction to Estrace Vaginal Cream Drug Interactions

Estrace® Vaginal Cream (estradiol vaginal cream) can potentially interact with several medicines. Some of the medicines that may lead to Estrace Vaginal Cream interactions include:
 
  • Barbiturates, including, but not limited to:

 

    • Butalbital (Fioricet®, Fiorinal®)
    • Pentobarbital (Nembutal®)
    • Phenobarbital (Luminal®)

 

  • Certain antifungals or antibiotics, including:

 

    • Clarithromycin (Biaxin®)
    • Erythromycin (Ery-Tab®)
    • Isoniazid (Nydrazid®)
    • Itraconazole (Sporanox®)
    • Ketoconazole (Nizoral®)
    • Miconazole
    • Telithromycin (Ketek®)

 

 

 

  • Rifamycin antibiotics, including rifabutin (Mycobutin®), rifampin (Rifadin®), and rifapentine (Priftin®)
  • Some seizure medications, such as:

 

 

 

 

Estrace Vaginal Cream Drug Interactions Article Continues on Next Page >
 

Estrace Vaginal Cream Information
Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD
Estrace Vaginal Cream
Estrace Vaginal Cream Side Effects
Estrace Vaginal Cream Uses
Estrace Vaginal Cream Dosage
Estrace Vaginal Cream Drug Interactions
Estrace Vaginal Cream Warnings and Precautions
Estrace Vaginal Cream Overdose
Estrace Vaginal Cream and Pregnancy
Estrace Vaginal Cream and Breastfeeding
Generic Estrace Vaginal Cream
 
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