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Enjuvia and Pregnancy
The FDA has classified Enjuvia as a pregnancy Category X medication, meaning that it should not be used during pregnancy. Although Enjuvia does not appear to increase the risk of birth defects or other problems, there is no legitimate medical reason for pregnant women to use this medication. It is only approved for use in postmenopausal women. If you are using Enjuvia and pregnancy occurs, contact your healthcare provider for further instructions.
Enjuvia® (conjugated estrogens) is a prescription estrogen medication that is used to treat menopausal symptoms. It is not approved for any use in pregnant women. There is also no accepted medical reason for pregnant women to use Enjuvia.
The U.S. Food and Drug Administration (FDA) uses a pregnancy category system to classify the possible risks to a fetus when a specific medicine is taken during pregnancy. Pregnancy Category X is given to medications that should not be used during pregnancy, usually due to serious problems that could occur (such as birth defects or miscarriages).
Although Enjuvia is a Category X medication, estrogen medications like Enjuvia do not appear to increase the risk of birth defects or other problems. However, because the risks are not fully understood (and because there is no accepted, legitimate medical reason for pregnant women to use Enjuvia), it should not be used during pregnancy.
Enjuvia should not intentionally be used during pregnancy and is not approved for any use in women of childbearing potential. It is only approved for use in postmenopausal women. If you inadvertently used Enjuvia for a while before realizing you were pregnant, it will probably not cause any problems (although you should discuss this with your healthcare provider). If you think you may be pregnant, you should contact your healthcare provider for further instructions.
Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD



