Drugs That Can Interfere With Divigel

Divigel Interactions Explained

The following sections explain in detail the potentially negative interactions that can occur when Divigel is combined with any of the drugs listed above.
 
Barbiturate Medications
Barbiturates may cause your body to metabolize the hormones in Divigel too rapidly, leading to low levels of Divigel in the body. This can make Divigel less effective, but it is not a serious drug interaction.
 
Cyclosporine (Gengraf, Neoral, Sandimmune)
Divigel may increase the level of cyclosporine in your blood, increasing the chance of side effects of cyclosporine. Talk with your healthcare provider before taking these medications together. You may need a lower cyclosporine dose, or you may need to switch to one of the many Divigel alternatives.
 
Protease Inhibitors
Protease inhibitors may decrease the ability of your liver to metabolize Divigel, leading to high levels of Divigel in the body. This may increase the risk of Divigel side effects. Check with your healthcare provider before combining Divigel with a protease inhibitor.
 
Rifamycin Antibiotics
Rifamycin antibiotics may cause your body to metabolize the hormones in Divigel too quickly, leading to low levels of Divigel in the body. Although this can make Divigel less effective, it is not a dangerous drug interaction.
 
Some Seizure Medications
Some seizure medications may cause your body to metabolize the hormones in Divigel too quickly, leading to low levels of Divigel in the body. Although this can make Divigel less effective, it is not a dangerous drug interaction.
 
St. John's Wort
St. John's wort (a commonly used herbal supplement) may cause your body to metabolize the hormones in Divigel too quickly, leading to low levels of Divigel in the body. Although this can make Divigel less effective, it is not a dangerous drug interaction.
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