Divigel and Pregnancy

Pregnant women should never intentionally use Divigel. Pregnancy problems could occur if a pregnancy Category X medication (such as Divigel) is used in pregnant women. Since there is no legitimate medical reason for a pregnant woman to use the drug and the risks are not fully known, Divigel should be avoided during pregnancy. If you are using Divigel and pregnancy occurs, notify your healthcare provider.

Can I Use Divigel During Pregnancy?

Divigel® (estradiol gel) is a prescription estrogen medication approved only for menopausal women. Pregnant women should not intentionally use Divigel, as there is no accepted medical reason for pregnant women to use this medication.

Divigel and Pregnancy Category X

The U.S. Food and Drug Administration (FDA) uses a pregnancy category system to classify the possible risks to a fetus when a specific medicine is taken during pregnancy. Pregnancy Category X is given to medications that should not be used during pregnancy, usually due to serious problems that could occur (such as miscarriages or severe birth defects). For Category X medications, the possible risks always outweigh the potential benefits in pregnant women.
Although Divigel is a Category X medication, it does not appear to increase the risk of birth defects or other problems. However, because there is no accepted, legitimate medical reason for pregnant women to use Divigel and because the risks are not fully understood, it should not be used during pregnancy. Estrogen medications (including Divigel) are not effective for preventing miscarriages or any other problems in pregnancy.

Divigel and Pregnancy: Final Thoughts

Divigel is not approved for any use in pregnant women. If you inadvertently used Divigel for a while before you realized you were pregnant, it will probably not cause any problems (although you should discuss this with your healthcare provider). If you think you may be pregnant, you should contact your healthcare provider for further instructions.
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