All of the patents for Depo-Estradiol (estradiol cypionate) have expired, and a generic form of the medication is currently available. The FDA has assigned generic Depo-Estradiol an "AO" rating, meaning that the generic medication is equivalent to the brand-name medication. However, generic medications are allowed to have different inactive ingredients, which can cause problems for people with certain allergies.
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Depo®-Estradiol (estradiol cypionate) is a prescription estrogen hormone replacement medication. It is approved for the following uses:
- Treating menopausal symptoms, such as night sweats or hot flashes
- Replacing hormones in younger women whose ovaries do not produce enough estrogen.
Depo-Estradiol is made by Pfizer, Inc. The patents for Depo-Estradiol have expired, and generic Depo-Estradiol is currently available.
At this time, generic Depo-Estradiol is made by Consolidated Midland Corporation. It comes in one strength (5 mg of estradiol cypionate per mL).
The generic version of Depo-Estradiol has been given an "AO" rating by the United States Food and Drug Administration (FDA), meaning that there is no reason to suspect that it should be any different from brand-name Depo-Estradiol. It is easier to make generic injectable medications that are completely equivalent to their brand-name counterparts, compared to tablets or other dosage forms.
However, generic medications are allowed to have different inactive ingredients than the brand-name medication. This might include fillers, dyes, or other ingredients that may cause problems for people with allergies or sensitivities.