Depo-Estradiol Drug Interactions

Before starting Depo-Estradiol, make sure to talk to your healthcare provider about any other medications you are taking. Drug interactions may occur if Depo-Estradiol is combined with certain medications, such as some antibiotics, seizure medications, and thyroid medicines. Some of these Depo-Estradiol drug interactions may cause your body to metabolize the medications differently than intended, possibly increasing your risk of side effects or other problems.

An Introduction to Depo-Estradiol Drug Interactions

Even though Depo®-Estradiol (estradiol cypionate) is not taken by mouth, it has the potential to interact with numerous other medications. Some of the medicines that may lead to Depo-Estradiol interactions include:
 
  • Barbiturates, including (but not limited to):

 

    • Butalbital (Fioricet®, Fiorinal®)
    • Pentobarbital (Nembutal®)
    • Phenobarbital (Luminal®)
    • Secobarbital (Seconal®

 

  • Certain antifungal medications or antibiotics, such as:

 

    • Clarithromycin (Biaxin®)
    • Erythromycin (Ery-Tab®)
    • Isoniazid (Nydrazid®)
    • Itraconazole (Sporanox®)
    • Ketoconazole (Nizoral®)
    • Miconazole
    • Telithromycin (Ketek®

 

  • Certain seizure medications, such as:

 

 

 

 

  • Rifamycin antibiotics, including rifabutin (Mycobutin®), rifampin (Rifadin®), and rifapentine (Priftin®)
  • St. John's wort (Hypericum perforatum), an herbal supplement
  • Thyroid replacement medications, including:

 

 

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Depo-Estradiol Drug Information

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