Delestrogen is an estrogen medication used for treating several conditions. Specifically, it is approved to treat certain menopausal symptoms (such as hot flashes, night sweats, or vaginal problems), hormone deficiencies, and advanced prostate cancer. It is a long-acting prescription drug that is typically injected once a month by your healthcare provider. Potential side effects include nausea, headaches, and stomach pain.

What Is Delestrogen?

Delestrogen® (estradiol valerate) is a prescription hormone replacement medication that contains estrogen. It comes in the form of a long-acting injection that is injected into a muscle, usually once a month. It is approved for the following uses:
  • Treating menopausal symptoms, such as hot flashes, night sweats, or vaginal symptoms
  • Replacing hormones in younger women whose ovaries do not produce enough estrogen (or who have had their ovaries removed)
  • Reducing the symptoms of advanced prostate cancer.
(Click Delestrogen Uses for more information on what this medication is used for, including possible off-label uses.)

Who Makes It?

Delestrogen is made by JHP Pharmaceuticals, LLC.

How Does Delestrogen Work?

Delestrogen contains estradiol, a hormone that is the predominant estrogen in premenopausal women. This medication helps to relieve menopausal symptoms by replacing the estrogen that the ovaries no longer produce.
Very high doses of estrogens (such as Delestrogen) can work to relieve the symptoms of advanced prostate cancer. For prostate cancer, Delestrogen works by suppressing testosterone and other male hormones that "feed" prostate cancer.
Delestrogen is formulated in oil to make the injection long-acting.
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Delestrogen Medication Information

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