Delestrogen Drug Interactions

If you combine certain medications (such as barbiturates, antibiotics, or thyroid medicines) with Delestrogen, drug interactions could occur. Taking these medications together may affect the levels of Delestrogen in your body, which can increase your risk of developing side effects or cause other problems. Although some of these interactions with Delestrogen are not serious, make sure to talk to your healthcare provider before combining any of these medications.

 

An Introduction to Delestrogen Drug Interactions

Delestrogen® (estradiol valerate) has the potential to interact with numerous other medications, even though Delestrogen is not taken by mouth. Not all of the Delestrogen drug interactions are serious. Some of the medicines that may lead to Delestrogen interactions include:
 
  • Barbiturates, including (but not limited to):

 

    • Butalbital (Fioricet®, Fiorinal®)
    • Pentobarbital (Nembutal®)
    • Phenobarbital (Luminal®)

 

  • Certain antifungal medications or antibiotics, such as:

 

    • Clarithromycin (Biaxin®)
    • Erythromycin (Ery-Tab®)
    • Isoniazid (Nydrazid®)
    • Itraconazole (Sporanox®)
    • Ketoconazole (Nizoral®)
    • Miconazole
    • Telithromycin (Ketek®)

 

  • Certain seizure medications, such as:

 

 

  • Cyclosporine (Gengraf®, Neoral®, Sandimmune®)
     
  • Protease inhibitor HIV medications, such as:

 

 

  • Rifamycin antibiotics, including rifabutin (Mycobutin®), rifampin (Rifadin®), and rifapentine (Priftin®)
     
  • St. John's wort (Hypericum perforatum), an herbal supplement
     
  • Thyroid replacement medications, including:

 

 

(Delestrogen Drug Interactions Continued: Page 2)
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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;